Plasma leptin is associated with amyloid CSF biomarkers and Alzheimer's disease diagnosis in cognitively impaired patients

M Lilamand, E Bouaziz-Amar… - The Journals of …, 2023 - academic.oup.com
plasma leptin levels and the diagnostic groups, with regard to the stage of … , leptin levels
were strongly influenced by gender and body composition, and we observed gender differences

Nonobese male patients with Alzheimer's Disease are vulnerable to decrease in plasma leptin

J Tian, T Wang, K Jia, L Guo… - Journal of Alzheimer's …, 2022 - content.iospress.com
… a therapeutic potential of leptin-boosting agents for the … in plasma leptin levels in females
regardless of AD diagnosis, … sex-related leptin regulation in AD patients and subjects at risk …

Impact of serum leptin and adiponectin levels on brain infarcts in patients with mild cognitive impairment and Alzheimer's disease: a longitudinal analysis

G Carbone, L Bencivenga, MA Santoro… - Frontiers in …, 2024 - frontiersin.org
… The cohort of subjects extracted from ADNI database for this study … with serum leptin levels
in our population were age, gender, BMI, … differ among the three diagnostic groups. However, …

Association between adipokines and biomarkers of Alzheimer's disease: a cross-sectional study

L Letra, P Matafome, T Rodrigues… - Journal of …, 2019 - content.iospress.com
… of the disease, as well as gender differences that may contribute to the … We included 53
patients with a probable diagnosis of … of adiponectin and leptin among MCI and AD subjects. Box …

[HTML][HTML] The role of leptin and adiponectin in obesity-associated cognitive decline and Alzheimer's disease

L Forny-Germano, FG De Felice… - Frontiers in …, 2019 - frontiersin.org
… disorders may prove of major relevance to diagnostic, prevention and therapy. … of leptin in
the brain are subject to regulation by local leptin production, circulating leptin levels and leptin

[HTML][HTML] Plasma leptin, but not adiponectin, is associated with cognitive impairment in older adults

I Feinkohl, J Janke, AJC Slooter, G Winterer… - …, 2020 - Elsevier
… With leptin as a known promoter of atherosclerosis and inflammation, our findings point
to a pathogenic role of leptin in age-related cognitive impairment that may be limited to non-…

Assessing adipokines as potential biomarkers of dementia, Alzheimer's disease, and mild cognitive impairment: a systematic review and meta-analysis

I Garcia-Garcia, M Narvaez, NG Casares - 2022 - osf.io
lower blood leptin and higher resistin levels than cognitively … associated with the diagnostic
and with the prospective risk of … serum and plasma: findings from TARC and ADNI. PloS One, …

[HTML][HTML] … on baseline and longitudinal positron emission tomography measurements of the cerebral metabolic rate for glucose in amnestic mild cognitive impairment

CM Weise, K Chen, Y Chen, V Devadas… - Frontiers in Aging …, 2022 - frontiersin.org
… with a diagnosis of amnestic mild cognitive impairment (aMCI), … data from different sites
participating in the ADNI trial, we … , further research including healthy subjects is required to …

[HTML][HTML] Consequences of metabolic disruption in Alzheimer's disease pathology

JC Ryu, ER Zimmer, P Rosa-Neto, SO Yoon - Neurotherapeutics, 2019 - Elsevier
… appears limited in diagnosing asymptomatic individuals as … The inclusion of mild cognitive
impairment (MCI) subjects, a … that lower serum leptin levels were associated with cognitive

[HTML][HTML] Inexpensive, non-invasive biomarkers predict Alzheimer transition using machine learning analysis of the Alzheimer's Disease Neuroimaging (ADNI) …

JF Beltran, BM Wahba, N Hose, D Shasha, RP Kline… - PloS one, 2020 - journals.plos.org
diagnostics in the literature were not used in this analysis; since the measurements were not
available for enough of the subjects at different ADNILeptin, insulin, C Reactive protein and …